Learn to use key bioinformatics databases and tools for sequence and structure analysis.
Course Description
Bioinformatics plays a crucial role in the storage, search, and analysis of biomolecular sequence and structure data. A significant amount of data is now available on the web, along with software tools for data search and analysis. It is essential that professionals working with biological sequences or structures in public and private sectors are knowledgeable about these databases and tools.
This practical course introduces the main public domain tools, databases and methods used in bioinformatics, including DNA and protein databases such as Genbank and PBD, software tools such as BLAST, and methods for aligning sequences. Topics include multiple alignment, phylogenetic analysis, microarrays and system biology. The course emphasizes the needs of the user of bioinformatics tools and databases, rather than complex algorithm development and advanced computational methods.
The course includes computer lab exercises and online demonstrations of the various databases and tools on the web. It is intended both for life scientists and computer engineers and is the recommended first course for those wanting to gain skills in bioinformatics.
Topics
- The subspecialties of bioinformatics
- Sequence alignment
- The basics of molecular biology
- Single nucleotide polymorphisms and genome-wide association studies
Additional Information
We will download the Sars-CoV-2 reference genome from the National Center for Biotechnology Information (NCBI) database; do BLAST to compare sequence similarity with bat RaTG13 CoV; use Clustal Omega, MUSCLE and T-COFFEE for multiple sequence alignment
Professional Credit
黑料不打烊 EXTENSION Approved by the California Board of Registered Nursing, Provider Number 13114, for 30 contact hours
- Online Traditional Complete online with instructor-set deadlines.
Online Traditional courses have a structured learning environment and fixed deadlines. This course is largely self-study with instructor guidance and includes online learning modules, assignments, and/or quizzes. All course materials and assignments will be available on Canvas, our learning management system.
For this section, student access begins on September 8, but you may still enroll until October 14. All course work must be completed by 11:59 pm on December 9, 2025.
Electronic Course Materials: You will be granted access in Canvas to your course site and course materials approximately 24 hours prior to the published start date of the course.
